Job Description

Scientist

1 year contract to potential hire

We are seeking an experienced biophysical/SPR Scientist to support our early antibody and peptide discovery programs using label-free technologies, such as Biacore and Octet BLI, to measure binding affinities, off-rates, and perform epitope binning and competition experiments. The successful individual will work in a cross-functional setting to execute assays to deliver robust and high-quality decision-making data. This laboratory position requires excellent scientific, technical and laboratory skills, strong organizational and communications skills, and enthusiasm in contributing to a fast-paced organization focused on discoveries of novel and differentiated therapeutic candidates.

Duties

• Utilize your experience with Biacore SPR and Octet BLI methodologies to execute and analyze SPR and BLI experiments to determine antibody/peptide affinity (KD), kinetics, epitope binning, pH dependence and dual-target engagement of monospecific and bispecific antibodies, scFv, Fabs and peptides.
• Apply your extensive knowledge of Biacore Insight and Octet Analysis software for data analysis
• Apply QC parameters to data and perform basic troubleshooting as necessary.
• Prepare high-quality data reports and presentations for project meetings.
• Perform regular maintenance of SPR and BLI instruments.
• Collaborate with scientists in a highly matrixed environment across multiple therapeutic areas and functional teams.

Qualifications

• BS with 4+ years, MS with 2+ years, or PhD
• Must have experience with measuring antibody/protein binding kinetics, pH dependent and dual engagement binding studies using Biacore SPR and Octet BLI methods.
• Experience with obtaining epitope binning and binding/competition binding studies using Octet BLI methods.
• Ability to QC and troubleshoot experiments.
• Collaborative and highly motivated

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